Doctoral Fellow – Cellular and developmental biology

Job title:

Doctoral Fellow – Cellular and developmental biology

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Job description

Offer DescriptionGenome and proteome integrity are crucial for proper embryo development, but how both are monitored across lineage specification remains an open question. We have recently identified that morphogenetic and patterning signals regulate DNA replication dynamics and chromosome segregation fidelity in a lineage-specific manner (De Jaime-Soguero et al. Nature Communications, 2024; PMID 39191776). These findings suggest that specific lineages respond and mitigate differently replicative stress. We seek a motivated doctoral researcher to investigate developmental resilience during early embryogenesis and lineage specification towards other stress sources. Our recently formed group (De Jaime-Soguero lab, IRIBHM-ULB) has expertise in cellular signaling and quantification of genome stability, pluripotency and early lineage specification in 2D, novel 3D stem cell-based embryo models and ex vivo mouse embryo experimentation. We collaborate with Isabelle Migeotte lab at IRIBHM, which has long-standing expertise in gastrulation and whole-embryo live imaging.Qualification profileYou hold a MsC in Life Sciences or Bioinformatics and have a strong interest in molecular, cell or developmental biology. Experience with cloning and/or R coding for bioinformatic analysis is a plus. You have strong analytical and communication skills, are enthusiastic and critical thinker. Fluency in English is required, as well as to be able to work well in an international environment. Grades during the MsC will be taken in account during the selection.We offerA 1-year funded PhD contract with the possibility of extension. During this time, the candidate is expected to apply for PhD fellowship programs under the support of IRIBHM. Our laboratory offers: i) a healthy lab culture and lively international environment, with English as working language, ii) access to advanced training in scientific and professional skills, iii) supervision and support tailored to your career perspectives, iv) access to state-of-the-art core facilities at ULB (microscopy, flow cytometry, sequencing) and v) interdisciplinary collaborations involved.Why to join IRIBHM and come to live in Brussels?IRIBHM-J.E. Dumont is a multidisciplinary research institute at the Université Libre de Bruxelles (ULB, Belgium) with a focus in diverse topics such as signal transduction, development, neuroscience, cancer and computational biology ( ; our group page is under construction). At the heart of Europe, Brussels is the largest student city in Belgium welcoming 160 different nationalities, a vibrant, tolerant and international capital.How to apply:Send your application to Anchel de Jaime-Soguero ( ), with the subject lane: De Jaime-Soguero lab PhD application. Attach: (1) Your BsC and MsC transcripts, (2) a detailed CV, (3) the contact information of two previous mentors/supervisors, and (4) a cover letter stating your interest in our lab and project. Applications will be evaluated on a rolling basis, until the position is filled.Applications sent after 31th of January 2025 will not be considered. The starting date expected is March 2025 onwards (to be discussed).Where to apply E-maildejaimesoguerolab@gmail.comRequirementsResearch Field Biological sciences Education Level Master Degree or equivalentResearch Field Medical sciences Education Level Master Degree or equivalentSkills/QualificationsYou hold a MsC in Life Sciences or Bioinformatics and have a strong interest in molecular, cell or developmental biology. Experience with cloning and/or R coding for bioinformatic analysis is a plus. You have strong analytical and communication skills, are enthusiastic and critical thinker. Fluency in English is required, as well as to be able to work well in an international environment. Grades during the MsC will be taken in account during the selection.Languages ENGLISH Level ExcellentAdditional InformationBenefitsA 1-year funded PhD contract with the possibility of extension. During this time, the candidate is expected to apply for PhD fellowship programs under the support of IRIBHM. Our laboratory offers: i) a healthy lab culture and lively international environment, with English as working language, ii) access to advanced training in scientific and professional skills, iii) supervision and support tailored to your career perspectives, iv) access to state-of-the-art core facilities at ULB (microscopy, flow cytometry, sequencing) and v) interdisciplinary collaborations involved.Eligibility criteriaThe motivation of the candidate, the grades during the BsC and the MsC, previous experience in other laboratories and the time after MsC graduation will be taken in account for selection.Selection processPreselected candidates will be invited to an online interview in a first phase. If succeed, the candidate will be invited to a second interview in person at IRIBHM, where he/she will be able to visit the institute and meet future colleagues.Work Location(s)Number of offers available 1 Company/Institute IRIBHM-JE Dumont Institute Country Europe City Brussels Postal Code 1170 Street Route de Lennik 808 GeofieldContact CityBrussels WebsiteStreetAnderlecht Postal Code1070STATUS: EXPIREDShare this page

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Location

Brussel

Job date

Wed, 27 Nov 2024 01:48:33 GMT

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