ERC Proof-of-Concept Funded Project: Novel inhibitors for obesity-associated liver cance

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ERC Proof-of-Concept Funded Project: Novel inhibitors for obesity-associated liver cance

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Offer DescriptionThe Signal Transduction and Metabolism Laboratory ( ) led by Dr Esteban Gurzov, the Redox Signaling laboratory ( ) led by Prof. Joris Messens, and the Organic Chemistry Research Group led by Dr Steven Ballet ( ) seeking a highly motivated PhD student to develop and explore novel inhibitors for obesity-associated liver dysfunction and hepatocellular carcinoma. The successful applicant will be part of joint PhD project funded by the European Research Council Proof-of-Concept (PI Gurzov).Project description:The project will take advantage of in silico drug design, chemical synthesis, biochemical assays, hepaticcancer cell models, bioinformatics and human liver specimen analysis. The objective is to identify novel molecules that can prevent or reverse the mechanisms by which obesity drives the development of hepatocellular carcinoma, paving the way for innovative therapeutics to combat this disease.Join Our Joint PhD Program!Embark on a journey in an international, world-leading environment dedicated to creative science. We foster research excellence and drive discoveries in metabolic diseases through collaborative teams of experts.Why Join Us?· We are committed to scientific rigor and reproducible findings, shaping the future of metabolic research.· Our vision is to translate fundamental science into clinical applications through collaboration between scientists, physicians, and industry leaders.Candidate Profile:· Bachelor’s and Master’s degrees in Bioengineering, Pharmaceutical Chemistry, or Chemical Biology.· Experience in chemical design/engineering.· Advantageous: Experience with (in silico) drug screening.· Advantageous: Experience with biochemistry assays.· Advantageous: Experience with models of obesity, cancer, or liver dysfunction.· Ability to work independently and collaboratively in a team.· Excellent organizational and time management skills.· Proficiency in spoken and written English.· High motivation, flexibility, and innovative, creative thinking.Come and join us in making groundbreaking contributions to metabolic research!Interested ?Applications should be sent directly to , , andEsteban N. Gurzov, PhD Director, Signal Transduction & Metabolism Laboratory Université libre de Bruxelles (ULB) 808 Route de Lennik B-1070 Brussels BelgiumTel: +32 2 555 8908Joris Messens, PhDFull ProfessorRedox Signaling LabVIB-VUB Center for Structural BiologyPleinlaan 2, building E, 4th floor1050 BrusselsBelgium+32478911288Steven Ballet, PhDFull Professor – Bioorganic ChemistryResearch Group of Organic ChemistryDepartments of Bioengineering Sciences and ChemistryVrije Universiteit Brussel (VUB)Pleinlaan 2, B-1050 Brussels, BelgiumT +32 (0)2 629 32 92Starting date: June 2025 (earliest).Deadline for the submission of applications: April 30th 2025Where to apply E-mailesteban.gurzov@ulb.beRequirementsResearch Field Medical sciences Education Level Master Degree or equivalentAdditional InformationWork Location(s)Number of offers available 1 Company/Institute ULB Country Belgium City Bruxelles Postal Code 1070 GeofieldContact CityBruxelles WebsiteStreetRoute de Lennik 808 – 1070 Bruxelles Postal Code1070STATUS: EXPIREDShare this page

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Brussel

Job date

Wed, 09 Apr 2025 05:34:16 GMT

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