Experienced PostDoc in Therapeutic NK cell engineering – DTU Bioengineering

Titlul postului:

Experienced PostDoc in Therapeutic NK cell engineering – DTU Bioengineering

Companie

Danmarks Tekniske Universitet

Descrierea postului

Job Category: VIP BJob Description:A 15 months position for an experienced postdoc is available within the research group ‘Biotherapeutic Glycoengineering and Immmunology’ headed by Professor Steffen Goletz and is funded by the DigitSTEM initiative. Our research group belongs to the Section of Medical Biotechnology at the Department of Biotechnology and Biomedicine.The position will be available from 1st January 2026.In our research group, we apply and develop advanced next generation antibody engineering as well as cellular and molecular glycoengineering technologies to elucidate the role of glycosylations within complex immunological networks and disease and to generate novel therapeutic approaches and drug candidates. Our main therapeutic interest is within immunooncology as well as infectious and lung diseases. One focus lies within cellular engineering and glycoengineering of human innate immune cells using gene editing for highly effective cell-based immunotherapeutics and the design and development of their manufacturing processes. Further focus areas are within next generation antibody engineering with bi-/ multispecific and multimodal antibodies, phage display technologies, exosome engineering and drug delivery, gene therapy, NK- and DC- cell based therapies and their mammalian bioprocess engineering and manufacturing. We also have a strong focus on innovation and entrepreneurship.The DigitSTEM initiative is a four-year stem cell focused research collaboration between The Technical University of Denmark (DTU), the The Novo Nordisk Foundation Center for Stem Cell Medicine (renew) at University of Copenhagen, and Bioneer A/S that aims at developing new in vitro disease models and therapeutics using human pluripotent stem cells (hPSCs).The current position focuses on engineering, glycoengineering and differentiation of human induced-pluripotent stem cells (iPSCs) into NK-cells, inducible gene-editing, exosome-based gene editing and bridging activities to our AI- assisted manufacturing approach.Responsibilities and qualifications
You as the postdoc will work with a team of Senior scientists, postdocs, and PhD students and in close collaboration with academic and industrial collaborators within the DigitSTEM initiative to establish a novel iPSC-derived NK-cell platform for next generation biotherapeutics.For this challenging project you have to be highly motivated and extensively trained and experienced with a track record in NK-cell biology and NK cell therapeutics, cellular immunology and assay technologies, in vitro 2D- and 3D cancer models, immunooncoloy and have extensive experience with immuncheckpoint and glycoengineered antibodies.A prior postdoc in this field is required. Knowledge and skills in cell engineering, glycoengineering, exosome-based gene delivery, and antibody and single-domain antibody engineering and proteomics will be of great advantage. Moreover, the successful postdoc is expected to contribute to inter connective team tasks as well as in teaching and supervision of PhD, BSc, and MSc students.The successful applicant should must hold a PhD degree in a relevant life-science discipline (cellular engineering, NK cell or stem cell biology, immunology, immunooncology or alike), have excellent communication skills and be extensively trained in immunology, stem cell biology, cellular engineering, cell culture systems, and computational data analysis.Assessment
The assessment of the applicants will be made by Professor Steffen Goletz.We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.The period of employment of the full-time position is 15 months. Starting date is January 1st 2026.You can read more about .Further information
Additional information may be obtained from Prof. Dr. Steffen Goletz, sgoletz@dtu.dkYou can read more about “the Department” at www.bioengineering.dtu.dkIf you are applying from abroad, you may find useful information on working in Denmark and at DTU at .Application procedure
Your complete online application must be submitted no later than 1 June 2025 (23:59 Danish time).Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• A letter motivating the application (cover letter)
• Curriculum vitae
• PhD certificate, Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale

Applications received after the deadline will not be considered.All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science- and biotech industries and point towards innovation, new businesses, and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus.Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Salariu așteptat

Locație

Kongens Lyngby, Hovedstaden – Lyngby, Midtjylland

Data jobului

Fri, 16 May 2025 23:51:37 GMT

Pentru a ne ajuta să urmărim efortul nostru de recrutare, vă rugăm să indicați în e-mailul/scrisoarea de intenție unde (jobsineu.net) ați văzut această postare de locuri de muncă.