Lab Scientist in Functional Proteomics

Job title:

Lab Scientist in Functional Proteomics

Company

Roche

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.That’s what makes us Roche.In Roche’s ), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.360 Labs Initiative at a GlanceThe 360 Labs are a new capability that is currently being built up within the ). The primary mission of this effort is to provide greater access and support for the use of cutting-edge biomedical research technologies by scientists across our discovery portfolio.The 360 Labs will deliver core scientific technologies, expertise and enabling activities, as well as facilitate knowledge sharing in close collaboration with our therapeutic areas and functions. Our ambition is to bring to life a thriving workplace environment, where your collaborative mindset is as valued as your professional expertise. Our goal is to act as an highly integrated ecosystem, supporting research and development, working collaboratively, and focused on fostering excellence and sustainability. Together, these efforts will serve to increase the speed, enhance the robustness and improve the sustainability of our exploratory research and early discovery activities.The OpportunityThe Proteomics & Metabolomics Technology Platform in the 360 Labs Initiative is seeking to add to its team an experienced, highly motivated, collaborative, and customer-centric lab-based scientific professional who is passionate about using functional proteomics approaches to support early stage drug discovery. The successful candidates will have a robust background in the life sciences, as well as broad experience in developing and applying complex proteomics workflows to investigate post translational processing, activation state, localisation and interactions of proteins of interest and across the proteome. You will work with a sense of urgency as a part of a matrix team, interacting with experts from each of our therapeutic disease areas and functions to advance drug discovery projects, and will participate in the continued evolution of the Proteomics & Metabolomics Technology Platform within the pRED organization. In this role you will:Plan, design, execute, and analyze hands-on experiments with a high degree of autonomy to interrogate the proteome for functional characterisation of disease biology, model system characterisation, and to support target assessment and identification of drug mechanisms;Develop, optimize, and implement innovative, integrated functional proteomics workflows covering experimental and computational aspects;Apply scientific rigor to optimize newly implemented and / or developed proteomics workflows to ensure high-quality FAIR data generation, collaborate with other laboratory and bioinformatics teams to analyze and interpret LC-MS-based proteomics data, be accountable for the timely generation of comprehensive project reports, and engage with stakeholders to present and discuss findings in a dynamic and flexible manner;You will embrace a culture of continuous learning by actively engaging with the latest scientific literature to stay at the forefront of emergent technologies/approaches in the functional proteomics field; present findings and updates to internal stakeholders and at scientific conferences (where appropriate), ensuring cutting-edge expertise is cultivated and maintained.Who you areYou hold a PhD degree in Biochemistry or a related field with additional professional experience, either as a post-doctoral researcher in an academic setting, or as a scientist in the pharmaceutical industry / biotech sector;You are a skilled experimentalist adept at designing and executing complex functional proteomics studies. You are experienced in the analysis of post-translational processing and modifications, studying protein localisation and protein-protein, protein-lipid or protein-R/DNA interactions using technologies such as: BioID, µMaps, LOPIT, APEX, TPP, IP-MS.You have exceptional competency in the processing, analysis, and interpretation of advanced proteomics datastreams, with the ability to integrate with other OMICS technologies being considered a plus.In addition to your scientific expertise and critical technical skills we are looking for candidates who are:Customer-focused with a drive for growth and a questioning mindset. Skilled in creative problem-solving, organization, and implementing innovative ideas efficiently in a fast-paced research context;Excellent communicators with a high fluency in English, a desire to continuously build a personal network and the ability to thrive in a dynamic, inclusive environment which gives you full accountability for your own contributions and development.Your LocationThis position is based in Basel.Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Expected salary

Location

Bâle

Job date

Fri, 27 Jun 2025 22:38:01 GMT

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