PhD Research Fellowship in Immunology
A 3-year PhD fellowship is available at the Department of Immunology, Oslo University Hospital. The position will be located in the lab of Prof. Ludvig Sollid and will be avaible from 01.10.2025. The research fellow will be enrolled in the PhD programme at the Faculty of Medicine, University of Oslo.The Sollid laboratory is focused on adaptive immune responses in Celiac Disease. Celiac disease is a common autoimmune disorder caused by dietary intake of gluten proteins. Celiac disease is well characterized and has the unique advantage that the antigens implicated in the pathogenesis are known. This project will explore an approach to selectively eliminate antigen-specific B cells in celiac disease. B-cell depletion therapies have emerged as a promising treatment for many autoimmune diseases. While elimination of all B cells is effective, this is a drastic intervention with immune deficiency and infection risk as a consequence. We will explore specific elimination of autoreactive B cells specific for the autoantigen in celiac disease, transglutaminase 2 (TG2), by developing so-called Bispecific AutoAntigen T-cell Engagers (BiAATEs). The PhD project is to develop these BiAATEs and to test their efficacy in eliminating TG2-reactive B cells using clinical samples from patients with celiac disease and unique mouse models generated in our laboratory. The work will be carried out in collaboration with other researchers and clinicians at Oslo University Hospital and will be jointly supervixsed by Professor Ludvig M. Sollid and Researcher Fleur du Pré. The research infrastructure includes access to a number of core facilities, including flow cytometry, microscopy and proteomics.
Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!Key tasks will include
Qualifications
The application must include
The application letter, CV and all other documents should be in English or in a Scandinavian language. In the evaluation of the applications, emphasis will be put on:
The applicant’s academic and personal qualifications to carry out the project within the allotted time frame. Good cooperative skills and the ability to successfully join in academic collaboration within and across disciplines. Experience with laboratory animals and the relevant techniques. Personal suitability and motivation for the position.Personal qualities
We are looking for:
We can offer
Kontaktinformasjon Ludvig M. Sollid , Professor and group leader,Arbeidssted Sognsvannsveien 20
0372 OsloNøkkelinformasjon: Arbeidsgiver: Oslo universitetssykehus HFReferansenr.: 4967875252
Stillingsprosent: 100%
Contract
Startdato: 01.10.2025
Søknadsfrist: 26.05.2025Kontaktperson for stillingenLudvig M. SollidProfessor and group leaderKopier e-postadresseOm bedriftenOslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.SektorOffentligNettsted
Oslo
Tue, 13 May 2025 22:23:08 GMT
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