Postdoc with focus on in vivo immune cell engineering against cancer

Titlul postului:

Postdoc with focus on in vivo immune cell engineering against cancer

Companie

Syddansk Universitet

Descrierea postului

Job Category: VIPJob Description:A position as postdoc (100% time) is vacant at the , the , , .The position is limited to 2 years with the possibility of extension.Research tasksThe position as a postdoc consists of research, mentoring, professional development, and guidance within the field tumor-immunology and cell therapy. The position focuses on in vivo reprogramming of immune cells using chimeric antigen receptor (CAR) constructs against glioblastoma. The position is funded via a Lundbeck Foundation Experiment grant. Ideal start date will be at or around August 01, 2025.The ideal candidate has experience with aseptic handling of primary human cells, culture, stimulation and transduction of T cells, and standard molecular biology methods, including cloning. Experience with flow cytometry and animal work is essential. Hands-on experience using cancer models in mice and handling NK cells and/or macrophages will also be appreciated. Knowledge about synthetic biology, CAR/protein engineering and mRNA-transduction is important, but not necessary. Experience with glioblastoma models will be a plus.The candidate will be placed within CITCO, at the Department of Clinical Immunology, which consists of several postdocs, PhD students and master students from different countries. We are looking for a candidate who is happy to work in a team and help train and mentor students as part of the project. The work-languages in the group are both Danish and English.Expectations of qualificationsThe applicant who is hired must have a Ph.D.-degree and documented research experience in on or more of the areas/fields mentioned below:

• Immunology, including experience with handling of primary immune cells, culture of these, flow cytometry and panel design, and standard immunological and molecular biology methods such as ELISA, and/or WB.
• Tumour biology, including knowledge about mouse models used for tumor-immunology will be important. Having an animal license and previous hands-on experience will be appreciated. Experience with glioblastoma mouse models and/or brain organoids, will be a plus.
• Cell-engineering, including experience with lentiviral transduction of primary immune cells is important. Knowledge about cloning and mRNA-transduction of cells is important. Understanding the process of cloning, handling of plasmids, and making lentivirus using cells is important. Experience with lipid nanoparticles (LNP) and mRNA will be a plus.

Further informationFor further information please contact Dr Mike B. Barnkob, e-mail: , phone: +45 27216890 or Head of Department at the Department of Clinical Research Rikke Leth-Larsen, e-mail: , phone: +45 65503477.Application deadlineJune 08, 2025, at 23.59 hrs. (CEST).Salary and terms of employmentThe applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations).ApplicationApplications must be submitted electronically using the link “Apply now” – see below.We strongly recommend that you read before you apply.Only applications written in English will be accepted for evaluation.The application must include (as PDF files) (please note that the application (the motivation letter) and CV must not exceed 10 MB in total):

• a motivation letter
• a detailed CV
• degree certificates (inclusive of Ph.D.-diploma)
• a complete and numbered list of publications
• 2 scientific peer-reviewed publications considered by the candidate as most important for this position. Please note that a copy of each publication must be attached as a pdf file.

• It is permitted to merge copies of the selected publications into a single PDF file.
• a detailed description of research experience

Please note that all the above-mentioned information must be included in the application.Incomplete applications with regards to the above-mentioned requirements will not be assessed.Applications may be shortlisted.If you experience technical problems, you must contact .Living and working in DenmarkForeign applicants will be offered as part of the employment.The (ISO) at SDU provides a variety of services for new employees, guests and people who consider applying for a job at the University of Southern Denmark.The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Salariu așteptat

Locație

Odense, Syddanmark

Data jobului

Fri, 25 Apr 2025 03:23:54 GMT

Pentru a ne ajuta să urmărim efortul nostru de recrutare, vă rugăm să indicați în e-mailul/scrisoarea de intenție unde (jobsineu.net) ați văzut această postare de locuri de muncă.