Senior Scientist / Principal Scientist, Radiobiology

Job title:

Senior Scientist / Principal Scientist, Radiobiology

Company

Work In Biotech

Job description

Summary
We are seeking a Senior/Principal Scientist in Radiobiology to join our growing Translational Biology team. We are also open to relocating new colleagues to Oslo! In this role, you will play a key part drug discovery and development to advance our innovative pipeline of targeted radiotherapies designed to revolutionize cancer treatment.Are you a highly motivated scientist with a passion for oncology research? Do you thrive in a collaborative environment and enjoy tackling complex scientific challenges? If so, we encourage you to apply!Responsibilities

• Manage, plan and execute in-vitro radiobiology studies to enable development of ARTBIO novel radioligand candidates from early Discovery to IND-readiness according to the company’s strategy.
• Design and execution of radiolabelling and analytical characterisation of radioligands and assessment of quality in close collaboration with the in-vitro radiochemistry team.
• Interface with project team and leadership to lead project goals and experimental design for drug development.
• Collaborate with external vendors and academic facilities for sourcing of reagents and execution of experimental activities.
• Provide mentorship and supervision to other ARTBIO preclinical team members so that experiments and projects are performed according to plan and internal ways of working.
• Support writing of regulatory documentation related to pre-clinical studies for RLT candidates selected for clinical development.
• Provide deep scientific expertise to guide selection of novel targets, candidate molecules and best experimental approaches to address relevant, scientific questions.
• Develop innovative solutions to mitigate research challenges & increase throughput and processes efficiency.
• Oversee data collection, analysis, interpretation, reporting and presentation.
• Multi-task and collaborate effectively with other scientists and research associates to accomplish goals on tight timelines. Ability to navigate in a start-up environment and adapt in the ‘unknown’
• Maintain compliance with lab documentation to enable collaboration among multinational project teams
• Analyse experimental results, brainstorm and troubleshoot findings thoughtfully and proactively
• Work seamlessly in matrixed environment to ensure technical support across programs

Qualifications & Education

• Phd or equivalent degree in Molecular Biology, Radioligand therapy development, Radiation Biology, or other relevant discipline with a significant laboratory-based skills component.
• At least 5 years working in research projects, particularly in drug discovery and in vitro testing of novel radioligands.
• Preferred industry experience, preferably radioligand therapy or oncology.
• Good English speaking and writing skills.
• Critical understanding of the principles of receptor pharmacology theory and experimental methodologies to assess ligand binding.
• Specific experience with radioligand therapy development, including radiolabelling and radiopharmaceutical applications.
• Proficiency in radiation safety practices and regulations, including working with open sources and radionuclides.
• Proven ability to develop, optimize, and validate novel in-vitro methods and techniques and creating and implementing high throughput screening methods to streamline research processes.
• Experience with Analytical Techniques such as use of gamma counters, Germanium Detectors, Dose calibrators, Thin Layer Chromatography and High-Performance Liquid Chromatography is a plus.
• Conducting and interpreting internalization assays to understand cellular uptake of radioligands.
• Strong analytical skills for processing and interpreting complex experimental data.
• Ability to work effectively within interdisciplinary teams and contribute to collaborative research efforts.
• Excellent communication skills for writing reports, preparing presentations, and publishing research findings.
• Experience managing research projects, timelines, and resources.
• Line management experience, including supervising and mentoring junior scientists.
• Demonstrated problem-solving abilities and innovation in addressing research challenges.
• Focus on the “we” rather than the “me”
• Motivated by patients, passionate about our company culture, inclusive and respectful of all colleagues

About Us
ARTBIO is a clinical-stage radiopharmaceutical company redefining cancer care by creating a new class of alpha radioligand therapies (ARTs). The unique ARTBIO approach selects the optimal alpha-precursor isotope (212Pb) and tumor-specific targets to create therapeutics with the potential for highest efficacy and safety. The company’s AlphaDirect™ technology, a first-of-its-kind 212Pb isolation method, enables a distributed manufacturing approach for the reliable production and delivery of ARTs. ARTBIO is advancing multiple pipeline programs with lead program AB001 currently in first in human trials. ARTBIO is shaped by a long-standing scientific legacy with nearly a century of pioneering work in radiation therapy conducted at the University of Oslo and Norway’s Radium Hospital. For more information, visit , and follow us on and .As an emerging, global biotech with locations in Boston, Massachusetts, Basel, Switzerland, London, England and Oslo, Norway, we take advantage of diverse scientific depth and insights which makes ARTBIO a unique place to work. We are driven by a desire to do better for cancer patients, lowering the burden of toleration and safety while at the same time raising the bar on clinical efficacy and duration.EEO Statement
ARTBIO is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Expected salary

Location

Oslo

Job date

Wed, 02 Oct 2024 07:46:55 GMT

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